In the aftermath of Christian’s attack by The Carver, Sean must forge a new partnership to keep the practice going. The police request Sean’s medical expertise for an obese woman named Momma Boone who has not left her home for over three years. Julia realizes it is time to make a decision about the future of her marriage.

Christian and Liz perform cosmetic surgery on an extraordinary ape to help her chances of reproducing. After learning that Ava is a trans gender woman, Matt questions his own sexuality and heads down a dark path. Tensions escalate at McNamara-Troy as Sean and Quentin, against Christian’s wishes, remove the tattoos of a gang member who wants to go straight..

Sean, Julia and Christian struggle to find a common solution as Matt spirals out of control. Christian performs surgery at his former fraternity house to help cover up a hazing ritual gone awry. When Christian’s open relationship with Kit--the sexy detective investigating the Carver’s activities--and Kimber loses its appeal, Christian asks Quentin to help ease Kit out of the threesome.

Christian has doubts about the latest Carver victim's story. The wife of an Alzheimer's patient requests extensive cosmetic surgery in order to find a way back into her husband's memories. Sean finds himself under investigation by Child Protective Services after Matt files a restraining order against him.

Christian becomes the prime suspect in the Carver case after police find a damning piece of evidence at the scene of the latest Carver attack. An HIV-positive man who suffers from facial wasting comes to McNamara-Troy to have his appearance restored to one of good health.

McNamara-Troy is in dire financial straits after Christian’s arrest. Gina returns and forms an unexpected business alliance with Julia. Sean and Christian reluctantly become involved in the gruesome case of a man who reassembled a female corpse from the appendages of other dead bodies.

A patient's extreme surgical request leaves Christian struggling between what the medical establishment says is right and what the patient says will make him feel whole. After leaving McNamara-Troy, Sean takes his surgery skills to the Witness Protection Program, where he transforms the appearance of a woman, Nicole Morretti, and her son, Austin. After a De La Mer Spa client reveals her startling beauty secret to Julia, Gina and Liz, they manufacture a new signature product--and hope the main ingredient remains a secret.

Sean questions his growing romantic feelings for Nikki when he learns the dark truth about her past. The request for plastic surgery from a patient with Down Syndrome moves Christian to make contact with his birth mother, Gail Pollack. Quentin woos Julia, who welcomes the attention.

Christian and Quentin’s mutual dislike deepens when they disagree over the ethics of a groundbreaking surgery that would enhance their medical reputations. Having fallen for Nikki, Sean can’t face letting her disappear into the Witness Protection Program without him. Christian gives Kimber a pre-nuptial ultimatum: give up her career in adult films or give up the wedding.

Christian and Kimber put the final touches on their wedding plans, but an unsigned prenuptial agreement casts a shadow of doubt across the occasion. Christian and Sean are stunned when Matt's new girlfriend compares plastic surgery to the work of Nazis.

Furious that Quentin is dating Julia, Sean resolves to do whatever it takes to force Quentin out of the practice. Christian claims to be fine after Kimber's sudden exit, but his relationship with a patient indicates otherwise. Sean worries Matt may be linked to a series of hate crimes against former plastic surgery patients.

Julia fights with her visiting mother and urges her to take an earlier flight back home to New York. The plane crashes on takeoff. As a guilt-ridden Julia awaits word of her mother in a makeshift hospital, she pitches in to comfort another woman's dying mother. Sean and Christian also try to save victims, but Quentin isn't there. At the spa earlier, he said something to Julia that really gets under her skin.

A shopping-mall Mrs. Santa Claus comes to McNamara-Troy for liposuction before the holidays, but a discovery during surgery jeopardizes her marriage to Mr. Claus. Julia must make a decision that could profoundly affect the rest of her life and the lives of her family. Ariel asks Matt to help her take drastic measures to alter her appearance.

The Carver's back in the picture in the third-season finale, and Christian tells Kit that Quentin should be her suspect. But first, Sean and Christian receive a bloody package. Its contents: Kimber's breast implants. Meanwhile, Julia learns something about her pregnancy; and Sean, Christian, Matt and the transsexual Matt had beaten up are involved in separate games of torture.

The Carver attacks sorority-house residents, Kit begins to close in on the elusive assailant, and the identity of the Carver is at last revealed. Elsewhere, Julia learns something about her condition; Sean, Christian, Matt and Cherry Peck are involved in separate games of torture.